Now, I don't really watch anime that much, so I don't know what's going on right now, but I don't have to. That face... just the way it's been executed makes me definitely know what she's feeling. Betrayal, embarrassment, confusion... just... AAAAAHH!!! Makes me want to cry! The girl is BEAUTIFUL, of course, not just the face, but the execution makes her amazing! The colors accompany this piece perfectly, especially that red face, it displays her emotion perfectly! The background is like the cherry on top, done excellently! Overall, I'd say this is one of my favorite pieces from you yet!
I have not used this media yet, but compared to your other Anime works i'd say job well done. Great Contrast of color's from both foreground into the Awesome background. I can only suggest giving more detailed thought to the underlining drawing's detail's. More Dimension or 3-d effect with regard to the accessories, i.e., shadow or indention of earring's, a more lazy,& natural lay of the necklace,and perhap's extending that thought to the clothes. Make a little more uneven, with some shadow. Overall great job!! Love your Blue Exorcist as well. Cheer's